The Family-Owned Restaurant Opens First Location In Denver

by Mark Smiley

Now Open: Los Dos Potrillos opened at 11 a.m. April 15, 2025, with a ribbon cutting ceremony. Los Dos takes over the space formerly occupied by Hacienda on South Colorado Boulevard. It is the first restaurant for the family in the city of Denver after decades in the suburbs.

Los Dos Potrillos, the family-owned Mexican restaurant known for its Mexican comfort food opened its first Denver location near Colorado Boulevard and I-25 at 4100 E. Mexico Avenue on April 15, 2025. The space was formerly occupied by Hacienda. The new Los Dos Potrillos has space for 253 patrons inside and 70 more on its patio.

They have been eyeing locations in Denver over the last several years but could not find the right area. “Whenever we look at any type of location, we always want to make sure it fits our way of going into any type of property,” said Danny Ramirez, CEO of Ramirez Hospitality Group, who owns Los Dos Potrillos. “We look forward to becoming a welcoming haven for our growing com­munity, offering the same quality, consistency, service, and commitment that defines the Los Dos family,” Ramirez.

“Expanding to Denver is an important step for us, allowing us to connect and serve a new group of diners. Our Los Dos family is excited about this growth and cannot wait to bring our delicious food and overall dining experience to a new community in such a centralized location,” added Luis Ramirez, COO and President.

Fresh Remodel: Los Dos Potrillos spent six months renovating what is now their sixth location in Colorado.

This milestone brings their family recipes and welcoming atmosphere to the heart of the Mile High City, marking a new chapter and the seventh Los Dos Potrillos full service restaurant opening in the Ramirez family’s journey.

Founded by Jose Ramirez in 2002, Los Dos Potrillos has grown from a single res­tau­rant in Centennial to a popular local brand with multiple locations across the Denver metro area. This Denver location represents the sixth addition to their growing family, joining the ranks of their other establishments.

The Colorado Boulevard location is the second largest footprint for the restaurant family next to the Castle Rock location which boasts 8,000 square feet of space.

The Denver Los Dos Potrillos will uphold the traditions and quality that have made Ramirez Hospitality Group a beloved household name across the region. Customers can expect the same welcoming atmosphere, excellent service, and Mexican comfort food that have earned the restaurant group a loyal following.

Taking over an existing Mexican restaurant made it a bit easier to move forward. “There wasn’t much to do since it was a Mexican restaurant,” said Daniel Ramirez. “All we had to do is come in and put our touch to it. We changed the outside and changed the interior. The kitchen is in immaculate condition. We just added our spice to it, literally,” Ramirez said with a smile.

For more information, visit www.los2potrillos.com.

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